Fig. 1

The patient’s vital signs during the anesthetic. 0 min, the beginning of anesthetic induction; 3 min, remimazolam and remifentanil were initiated; 4 min, rocuronium was administrated; 8 min, tracheal intubation and securing arterial line; 9 min, phenylephrine 0.1 mg; 10 min, ephedrine 8 mg; 11 min, remimazolam and remifentanil were discontinued; 13 min, phenylephrine 0.2 mg; 14 min, ephedrine 8 mg; 17 min, adrenaline 0.1 mg; 23 min, norepinephrine 0.1 mcg/kg/min, dobutamine 5 mcg/kg/min, and adrenaline 0.3 mg; 28 min, adrenaline 0.3 mg; 30 min, adrenaline 0.3 mg and hydrocortisone 100 mg; 31 min, famotidine 20 mg and hydroxyzine 25 mg. There were no data regarding blood pressure from 6 to 11 minutes after anesthesia induction, as non-invasive blood pressure monitoring was discontinued 6 minutes after anesthesia induction because we expected that it would be replaced by arterial blood pressure monitoring