Total cohort | Propensity score-matched cohort | |||||
---|---|---|---|---|---|---|
Group S | Group R | P | Group S | Group R | P | |
(n = 393) | (n = 169) | (n = 141) | (n = 141) | |||
Intraoperative variables | ||||||
Operation time (min) | 335 (166–498) | 159 (100–261) | < 0.001 | 166 (112–290) | 183 (111–293) | 0.99 |
Anesthesia time (min) | 417 (241–578) | 241 (174–356) | < 0.001 | 240 (189–370) | 257 (180–381) | 0.86 |
Fluid intake (mL) | 2750 (1500–4100) | 1640 (1110–2450) | < 0.001 | 1550 (1100–2400) | 1670 (1150–2600) | 0.39 |
Blood loss (mL) | 120 (24–360) | 50 (10–190) | 0 | 46 (10–156) | 60 (10–185) | 0.38 |
Urine output (mL) | 325 (135–615) | 130 (50–270) | < 0.001 | 200 (65–401) | 155 (55–300) | 0.2 |
Sevoflurane (%) | 1.4 (1.2–1.5) | 1.3 (1.1–1.5) | ||||
Remimazolam (mg/kg/h) | 0.72 (0.52–0.89) | 0.76 (0.56–0.89) | ||||
Remifentanil (μg/kg/min) | 0.15 (0.11–0.20) | 0.17 (0.12–0.21) | 0.04 | 0.15 (0.11–0.19) | 0.17 (0.12–0.22) | 0 |
Fentanyl (mg) | 0.15 (0–0.40) | 0.20 (0.10–0.35) | 0.15 | 0.20 (0.10–0.32) | 0.20 (0.10–0.35) | 0.44 |
Use of vasopressor | 357 (90.8%) | 137 (81.1%) | 0 | 129 (91.5%) | 115 (81.6%) | 0.02 |
Ephedrine (mg) | 10 (4–18) | 4 (0–8) | < 0.001 | 12 (4–20) | 4 (0–8) | < 0.001 |
Phenylephrine (mg) | 0.10 (0–0.50) | 0.05 (0–0.30) | 0.06 | 0.10 (0–0.50) | 0.05 (0–0.25) | 0.06 |
Dopamine (mg) | 0 (0–0) | 0 (0–0) | 0.3 | 0 (0–0) | 0 (0–0) | 0.45 |
Norepinephrine (mg) | 0 (0–0) | 0 (0–0) | 0.17 | 0 (0–0) | 0 (0–0) | 0.56 |
Incidence of IOH | 363 (92.4%) | 144 (85.2%) | 0.01 | 129 (91.5%) | 120 (85.1%) | 0.14 |
Cumulative hypotension time (min) | 335 (166–498) | 159 (100–261) | < 0.001 | 83 (39–144) | 55 (18–119) | 0.01 |