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Table 2 Intraoperative variables before and after propensity score matching

From: Effect of remimazolam versus sevoflurane on intraoperative hemodynamics in noncardiac surgery: a retrospective observational study using propensity score matching

 

Total cohort

Propensity score-matched cohort

Group S

Group R

P

Group S

Group R

P

(n = 393)

(n = 169)

 

(n = 141)

(n = 141)

 

Intraoperative variables

 Operation time (min)

335 (166–498)

159 (100–261)

 < 0.001

166 (112–290)

183 (111–293)

0.99

 Anesthesia time (min)

417 (241–578)

241 (174–356)

 < 0.001

240 (189–370)

257 (180–381)

0.86

 Fluid intake (mL)

2750 (1500–4100)

1640 (1110–2450)

 < 0.001

1550 (1100–2400)

1670 (1150–2600)

0.39

 Blood loss (mL)

120 (24–360)

50 (10–190)

0

46 (10–156)

60 (10–185)

0.38

 Urine output (mL)

325 (135–615)

130 (50–270)

 < 0.001

200 (65–401)

155 (55–300)

0.2

 Sevoflurane (%)

1.4 (1.2–1.5)

  

1.3 (1.1–1.5)

  

Remimazolam (mg/kg/h)

 

0.72 (0.52–0.89)

  

0.76 (0.56–0.89)

 

 Remifentanil (μg/kg/min)

0.15 (0.11–0.20)

0.17 (0.12–0.21)

0.04

0.15 (0.11–0.19)

0.17 (0.12–0.22)

0

 Fentanyl (mg)

0.15 (0–0.40)

0.20 (0.10–0.35)

0.15

0.20 (0.10–0.32)

0.20 (0.10–0.35)

0.44

 Use of vasopressor

357 (90.8%)

137 (81.1%)

0

129 (91.5%)

115 (81.6%)

0.02

 Ephedrine (mg)

10 (4–18)

4 (0–8)

 < 0.001

12 (4–20)

4 (0–8)

 < 0.001

 Phenylephrine (mg)

0.10 (0–0.50)

0.05 (0–0.30)

0.06

0.10 (0–0.50)

0.05 (0–0.25)

0.06

 Dopamine (mg)

0 (0–0)

0 (0–0)

0.3

0 (0–0)

0 (0–0)

0.45

 Norepinephrine (mg)

0 (0–0)

0 (0–0)

0.17

0 (0–0)

0 (0–0)

0.56

 Incidence of IOH

363 (92.4%)

144 (85.2%)

0.01

129 (91.5%)

120 (85.1%)

0.14

 Cumulative hypotension time (min)

335 (166–498)

159 (100–261)

 < 0.001

83 (39–144)

55 (18–119)

0.01

  1. Data are expressed as the median (interquartile range) or number (%) of patients
  2. IOH intraoperative hypotension, SMD standardized mean difference