Relationship between estimated and observed heparin sensitivity indices in cardiac and thoracic aortic surgery

JA Clinical Reports

Table 2 Results of multiple logistic analysis calculating odds ratios for heparin resistance (n = 590)

	Odds ratio (95% Confidence interval)	P value
Age	1.00 (0.98–1.02)	0.48
Female	0.71 (0.48–1.05)	0.09
Hemodialysis	2.35 (1.15–4.79)	0.01
Current smoking	0.82 (0.37–1.80)	0.62
Platelet	1.04 (1.01–1.08)	0.003
Prothrombin time-international normalized ratio	0.66 (0.27–1.59)	0.36
Antithrombin	1.00 (0.99–1.01)	0.54
Fibrinogen albumin ratio index	1.05 (1.01–1.10)	0.01
Baseline activated clotting time	0.97 (0.95–0;98)	< 0.001
Initial heparin dose (per unit/kg)	0.98 (0.97–0.99)	< 0.001

The explanatory model based on these variables had an area under the receiver operating characteristic curve of 0.70 (95% confidence interval, 0.60 − 0.75)