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Table 2 Coagulation capacity before and after administration of cryoprecipitate, intraoperative blood transfusion volume, and outcome

From: Effect of cryoprecipitate on an increase in fibrinogen level in patients with excessive intraoperative blood loss: a single-center retrospective study

 

Group A

(n = 36)

Group B

(n = 37)

Group C

(n = 11)

p

Pre-PTT (s)

16.0 (14.2–17.9)

17.6 (16.3–19.2) **

19.7 (17.4–24.0) **

0.003

Post-PTT (s)

14.2 (13.6–14.8)

14.4 (13.7–16.0)

14.1 (13.5–15.5)

0.37

Pre-APTT (s)

40.8 (37.5–49.9)

51.2 (43.5–109.5) **

85.2 (79.5–180.0) **

0.001

Post-APTT (s)

36.1 (33.3–38.1)

38.5 (32.3–45.4)

35.3 (32.0–60.4)

0.34

Transfusion (ml)

 RBC

1540 ± 420

2240 ± 1400*

4620 ± 1820****, ††††

< 0.0001

 FFP

960 ± 600

1800 ± 1200***

4680 ± 2400****, †††

< 0.0001

 PC

380 ± 180

480 ± 320**

520 ± 180**

0.001

30-day mortality, n (%)

3 (8)

5 (14)

0 (0)

0.39

  1. PTT partial thromboplastin time, APTT activated partial thromboplastin time, RBC red blood cell, FFP fresh frozen plasma, PC platelet concentrate
  2. *p < 0.05 vs. Group A, **p < 0.01 vs. Group A, ***p < 0.001 vs. Group A, ****p < 0.0001 vs. Group A, p < 0.05 vs. Group B, †††p < 0.001 vs. Group B, ††††p < 0.0001 vs. Group B