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Table 2 Coagulation capacity before and after administration of cryoprecipitate, intraoperative blood transfusion volume, and outcome

From: Effect of cryoprecipitate on an increase in fibrinogen level in patients with excessive intraoperative blood loss: a single-center retrospective study

  Group A
(n = 36)
Group B
(n = 37)
Group C
(n = 11)
p
Pre-PTT (s) 16.0 (14.2–17.9) 17.6 (16.3–19.2) ** 19.7 (17.4–24.0) ** 0.003
Post-PTT (s) 14.2 (13.6–14.8) 14.4 (13.7–16.0) 14.1 (13.5–15.5) 0.37
Pre-APTT (s) 40.8 (37.5–49.9) 51.2 (43.5–109.5) ** 85.2 (79.5–180.0) ** 0.001
Post-APTT (s) 36.1 (33.3–38.1) 38.5 (32.3–45.4) 35.3 (32.0–60.4) 0.34
Transfusion (ml)
 RBC 1540 ± 420 2240 ± 1400* 4620 ± 1820****, †††† < 0.0001
 FFP 960 ± 600 1800 ± 1200*** 4680 ± 2400****, ††† < 0.0001
 PC 380 ± 180 480 ± 320** 520 ± 180** 0.001
30-day mortality, n (%) 3 (8) 5 (14) 0 (0) 0.39
  1. PTT partial thromboplastin time, APTT activated partial thromboplastin time, RBC red blood cell, FFP fresh frozen plasma, PC platelet concentrate
  2. *p < 0.05 vs. Group A, **p < 0.01 vs. Group A, ***p < 0.001 vs. Group A, ****p < 0.0001 vs. Group A, p < 0.05 vs. Group B, †††p < 0.001 vs. Group B, ††††p < 0.0001 vs. Group B