Rapid detection of single nucleotide polymorphisms using the MinION nanopore sequencer: a feasibility study for perioperative precision medicine

JA Clinical Reports

Table 1 List of SNPs evaluated in this study

SNP	Gene	Full gene name	Clinical significance	Ref.
rs1045642	ABCB1	ATP binding cassette subfamily B member 1	A>G: increased susceptibility to PONV A>G: increased opioid dose requirement	[7, 8]
rs1799971	OPRM1	Opioid receptor mu 1	A>G: increased opioid dose requirement	[9,10,11]
rs2165870	CHRM3	Cholinergic receptor muscarinic 3	A>G: decreased susceptibility to PONV	[12, 13]
rs4369876	SCN9A	Sodium voltage-gated channel alpha subunit 9	C>A: decreased pain sensitivity	[14]
rs33985936	SCN11A	Sodium voltage-gated channel alpha subunit 11	C>T: increased pain sensitivity	[15]
rs140124801	KCNG4	Potassium voltage-gated channel modifier subfamily G member 4	C>T: decreased pain sensitivity	[16]