Positive end-expiratory pressure setting based on transpulmonary pressure during robot-assisted laparoscopic prostatectomy: an observational intervention study

JA Clinical Reports

Table 4 Changes in hemodynamic and cerebral oxygenation parameters during anesthesia

	After induction	Positive-pressure capnoperitoneum and Trendelenburg position					End of surgery
	After induction	PEEP0	PEEP5	PEEP10	PEEP15	PtpEEP0	End of surgery
Heart rate (bpm)	62 [60, 68]	62 [55, 66]	60 [57, 64]	60 [56, 63]	60 [55, 64]	62 [57, 66]	64 [55, 71]
mBP (mmHg)	78 [69, 80]	90 [79, 98]	80 [76, 88]	83 [73, 92]	77 [71, 83] ^*0	80 [77, 83]	77 [66, 85]
CI (L/min/m²)	1.9 [1.7, 2.3]	1.9 [1.8, 2.2]	2 [1.7, 2.1]	1.8 [1.7, 1.9]	1.6 [1.5, 1.9]	1.9 [1.6, 2]	2.3 [2, 2.9]
rSO₂(rt) (%)	64 [62, 68]	69 [65, 71]	69 [67, 73]	70 [68, 75]	72 [68, 74]	73 [70, 75]^*0	72 [68, 74]
rSO₂(lt) (%)	68 [67, 70]	69 [63, 75]	69 [67, 76]	71 [66, 77]	71 [67, 77]	73 [69, 78] ^*0	74 [68, 77]

mBP mean blood pressure, CI cardiac index, rSO₂ regional cerebral oxygen saturation, PEEP positive end-expiratory pressure
^*0P < 0.05 vs. PEEP0