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Table 4 Univariate analysis of characteristics, comorbidities, and laboratory data between patients with recovered and worsened respiratory condition

From: Treatment and outcome of COVID-19 patients in a specialized hospital during the third wave: advance of age and increased mortality compared with the first/second waves

  All (n = 581) Improved (n = 496) Worsened and died (n = 81) P value
Age (year) 71 (62−83) 78 (60−83) 79 (71−84) 0.02
Sex (male) 289 (50%) 233 (40%) 56 (69%) < 0.001
Body mass index (kg/m2) 23 (21−26) 23 (21−26) 24 (21−27) 0.02
Comorbidities
 Hypertension 210 (36%) 180 (36%) 30 (37%) 0.90
 Diabetes mellitus 121 (22%) 104 (21%) 17 (21%) 1.00
Laboratory data
 White blood cell count (× 109/L) 5.4 (4.1−7.1) 5.4 (4.1−7.1) 5.4 (4.2−7.2) 0.84
 Lymphocyte (× 109/L) 1.1 (0.8−1.4) 1.1 (0.8−1.5) 0.9 (0.7−1.2) 0.002
 Aspartate aminotransferase (U/L) 31 (23−43) 30 (22−41) 39 (28−49) < 0.001
 Alanine aminotransferase (U/L) 22 (14−36) 22 (14−36) 25 (17−37) 0.064
 Lactate dehydrogenase (U/L) 234 (195−304) 229 (193−298) 274 (223−372) < 0.001
 Creatinine (mg/dL) 0.76 (0.60−0.98) 0.75 (0.59−0.96) 0.86 (0.68−1.10) 0.004
 C-reactive protein (mg/dL) 2.6 (0.5−5.9) 2.2 (0.4−5.3) 5.8 (2.8−8.8) < 0.001
 Fibrinogen (mg/dL) 418 (337−505) 411 (328−505) 433 (373−538) 0.067
 D-dimer (μg/dL) 0.8 (0.6−1.4) 0.8 (0.6−1.1) 1.0 (0.8−1.7) 0.003
 Ferritin (ng/mL) 366 (176−721) 351 (168−699) 463 (229−1035) 0.004
  1. Data are expressed as the absolute value (percentage) or median (25−75% interquartile range)
  2. Laboratory data were obtained on the day of admission