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Table 4 Univariate analysis of characteristics, comorbidities, and laboratory data between patients with recovered and worsened respiratory condition

From: Treatment and outcome of COVID-19 patients in a specialized hospital during the third wave: advance of age and increased mortality compared with the first/second waves

 

All (n = 581)

Improved (n = 496)

Worsened and died (n = 81)

P value

Age (year)

71 (62−83)

78 (60−83)

79 (71−84)

0.02

Sex (male)

289 (50%)

233 (40%)

56 (69%)

< 0.001

Body mass index (kg/m2)

23 (21−26)

23 (21−26)

24 (21−27)

0.02

Comorbidities

 Hypertension

210 (36%)

180 (36%)

30 (37%)

0.90

 Diabetes mellitus

121 (22%)

104 (21%)

17 (21%)

1.00

Laboratory data

 White blood cell count (× 109/L)

5.4 (4.1−7.1)

5.4 (4.1−7.1)

5.4 (4.2−7.2)

0.84

 Lymphocyte (× 109/L)

1.1 (0.8−1.4)

1.1 (0.8−1.5)

0.9 (0.7−1.2)

0.002

 Aspartate aminotransferase (U/L)

31 (23−43)

30 (22−41)

39 (28−49)

< 0.001

 Alanine aminotransferase (U/L)

22 (14−36)

22 (14−36)

25 (17−37)

0.064

 Lactate dehydrogenase (U/L)

234 (195−304)

229 (193−298)

274 (223−372)

< 0.001

 Creatinine (mg/dL)

0.76 (0.60−0.98)

0.75 (0.59−0.96)

0.86 (0.68−1.10)

0.004

 C-reactive protein (mg/dL)

2.6 (0.5−5.9)

2.2 (0.4−5.3)

5.8 (2.8−8.8)

< 0.001

 Fibrinogen (mg/dL)

418 (337−505)

411 (328−505)

433 (373−538)

0.067

 D-dimer (μg/dL)

0.8 (0.6−1.4)

0.8 (0.6−1.1)

1.0 (0.8−1.7)

0.003

 Ferritin (ng/mL)

366 (176−721)

351 (168−699)

463 (229−1035)

0.004

  1. Data are expressed as the absolute value (percentage) or median (25−75% interquartile range)
  2. Laboratory data were obtained on the day of admission