Intra-operative intravascular effect of the difference in colloid solutions during acute normovolemic hemodilution

JA Clinical Reports

Table 2 Changes in variables during surgery

		Baseline	After ANH	After surgery	F	p-value
Hb, g/dL	DEX	12.5 ± 1.1	9.4 ± 1.5*	11.0 ± 1.5*^§#	3.520	0.0307
Hb, g/dL	HES	11.9 ± 0.9	9.0 ± 2.7*	9.9 ± 1.3*^§	3.520	0.0307
Plt, 10⁴/μL	DEX	24.5 ± 6.6	19.7 ± 6.0*	19.9 ± 6.1*	0.526	0.5913
Plt, 10⁴/μL	HES	22.6 ± 6.4	18.4 ± 5.2*	18.3 ± 5.0*	0.526	0.5913
Na, mmol/L	DEX	137.9 ± 2.5	137.0 ± 2.2*^#	136.3 ± 2.7*^§#	7.962	0.0004
Na, mmol/L	HES	138.3 ± 2.0	138.7 ± 2.2	137.8 ± 2.5^§	7.962	0.0004
K, mmol/L	DEX	3.7 ± 0.2	3.5 ± 0.3*	3.7 ± 0.4^§	1.244	0.2896
K, mmol/L	HES	3.7 ± 0.2	3.4 ± 0.2*	3.6 ± 0.3^§	1.244	0.2896
Cl, mmol/L	DEX	107.6 ± 2.3	109.8 ± 2.3*^#	109.0 ± 3.0*^§#	22.56	< 0.0001
Cl, mmol/L	HES	107.7 ± 2.0	112.3 ± 2.1*	111.0 ± 2.4*^§	22.56	< 0.0001
BE, mg/dL	DEX	1.8 ± 1.7	0.6 ± 1.6*^#	0.2 ± 1.7*^#	7.100	0.0010
BE, mg/dL	HES	0.8 ± 1.8	− 1.2 ± 1.7*	− 1.3 ± 1.6*	7.100	0.0010
Lac, mmol/L	DEX	0.8 ± 0.2	1.2 ± 0.5*^#	1.0 ± 0.5*^§#	23.03	< 0.0001
Lac, mmol/L	HES	0.7 ± 0.2	0.6 ± 0.2*^#	0.8 ± 0.5^§#	23.03	< 0.0001

The data are mean ± SD
*p < 0.01 vs. baseline, ^§p < 0.01 vs. after ANH, ^#p < 0.01 vs. HES
DEX dextran, HES hydroxyethyl starch, BE base excess, Cl chloride, Hb hemoglobin, K potassium, Lac lactate, Na sodium, Plt platelet count