Effect of droperidol addition to fentanyl-based intravenous patient-controlled analgesia on postoperative nausea and vomiting: a single-center retrospective cohort study

JA Clinical Reports

Table 1 Patient characteristics and operative variables according to droperidol use

	All patients (n = 588)	Without droperidol (n = 238)	With droperidol (n = 350)	P value
Age (years)	46 [38–58]	49 [40–61]	45 [37–55]	< 0.001
BMI (kg/m²)	21.5 [19.5–24.2]	21.5 [19.5–24.3]	21.6 [19.5–23.8]	0.794
Ever smoker	147 (25%)	66 (28%)	81 (23%)	0.207
ASA-PS (1/1E/2/2E/3/missing)	301/8/263/3/11/2	99/2/125/1/9/2	202/6/138/2/2/0	< 0.001
Malignancy	189 (32%)	69 (29%)	120 (34%)	0.177
Duration of surgery (min)	212 [147–312]	202 [152–289]	214 [147–322]	0.417
Concentration of fentanyl to be filled into ivPCA (μg/mL)	25 [20–25]	25 [20–25]	20 [20–25]	0.108
Total intraoperative fentanyl dose (μg)	250 [150–300]	250 [150–300]	250 [150–300]	0.380
Intraoperative antiemetic use	275 (47%)	80 (34%)	195 (56%)	< 0.001
Blood loss (mL)	25 [0–110]	25 [0–110]	25 [0–104]	0.973
Total intravenous anesthesia	95 (16%)	45 (19%)	50 (14%)	0.135

Continuous variables were presented as medians [interquartile range] and compared using the Mann-Whitney U test. Categorical variables were presented as numbers (percentage) and compared using the Pearson chi-square test or Fisher exact test, as appropriate. BMI body mass index, ASA-PS American Society of Anesthesiologists physical status classification, ivPCA intravenous patient-controlled analgesia