PMV (n = 93) | Non-PMV (n = 103) | p value | |
---|---|---|---|
Age (years; median [IQR]) | 73.0 [66.0–79.0] | 70 [59.0–79.0] | 0.19 |
Sex (male n, %) | 64 (68.8) | 65 (63.1) | 0.40 |
Comorbidities (n, %) | |||
Heart disease | 17 (18.3) | 30 (29.1) | 0.08 |
Respiratory disease | 9 (9.7) | 8 (7.8) | 0.63 |
Renal disease | 7 (7.5) | 7 (6.8) | 0.84 |
Cerebrovascular disease | 12 (12.9) | 10 (9.7) | 0.48 |
Type of admission to ICU (n, %) | |||
Scheduled | < 0.001 | ||
Elective surgery | 4 (4.3) | 23 (22.3) | |
Emergency | |||
Ward | 33 (35.5) | 14 (13.6) | |
Emergency department | 47 (50.5) | 46 (44.7) | |
Emergency surgery | 9 (9.7) | 20 (19.4) | |
Diagnosis at ICU admission (n, %) | |||
Surgical | |||
Neurosurgical disease | 0 (0.0) | 0 (0.0) | − |
Cardiovascular disease | 6 (6.5) | 24 (23.3) | < 0.001 |
Gastrointestinal disease | 6 (6.5) | 17 (16.5) | 0.03 |
Others | 1 (1.1) | 2 (1.1) | 0.62 |
Medical | |||
Acute respiratory disease | 43 (46.2) | 30 (29.1) | 0.01 |
Cardiovascular disease | 6 (6.5) | 24 (23.3) | 0.001 |
Septic shock | 10 (10.8) | 5 (4.9) | 0.12 |
Post-cardiac arrest syndrome | 10 (10.8) | 12 (11.7) | 0.84 |
Trauma | 9 (9.7) | 5 (4.9) | 0.19 |
Neuromuscular disease | 4 (4.3) | 0 (0.0) | 0.03 |
Central nervous system disease | 2 (2.2) | 3 (2.9) | 0.78 |
Others | 5 (5.4) | 11 (10.7) | 0.20 |
APACHE II score (mean ± standard deviation) | 25.6 ± 6.6 | 24.3 ± 6.6 | 0.16 |
Steroid use during MV (n, %) | 35 (37.6) | 19 (18.5) | 0.003 |
Neuromuscular blocker use during MV (n, %) | 7 (7.5) | 13 (12.6) | 0.24 |
Vasoactive drug use during MV (n, %) | 62 (66.7) | 69 (67.0) | 0.96 |
Continuous renal replacement therapy during MV (n, %) | 13 (14.0) | 7 (6.8) | 0.10 |
Spontaneous breathing trail within 21 days (n, %) | 38 (40.9) | 85 (82.5) | < 0.001 |
Tracheostomy (n, %) | 85 (91.4) | 6 (5.8) | < 0.001 |
Time from MV initiation to tracheostomy (days; median [IQR]) | 14 (9–18) | 9 (7–19) | 0.02 |
Duration of MV (days; median [IQR]) | 37.0 [27.0–62.0] | – | – |
ICU/HCU stay (days; median [IQR]) | 34.0 [25.0–49.5] | 7.0 [5.0–10.0] | < 0.001 |
Hospital stay (days; median [IQR]) | 74.0 [45.0–122.0] | 35 [17.0–51.0] | < 0.001 |
Hospital mortality (n, %) | 51 (54.8) | 22 (21.4) | < 0.001 |