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Table 1 Characteristics of the PMV and the non-PMV patients

From: Clinical features and outcomes of prolonged mechanical ventilation: a single-center retrospective observational study

  PMV (n = 93) Non-PMV (n = 103) p value
Age (years; median [IQR]) 73.0 [66.0–79.0] 70 [59.0–79.0] 0.19
Sex (male n, %) 64 (68.8) 65 (63.1) 0.40
Comorbidities (n, %)
 Heart disease 17 (18.3) 30 (29.1) 0.08
 Respiratory disease 9 (9.7) 8 (7.8) 0.63
 Renal disease 7 (7.5) 7 (6.8) 0.84
 Cerebrovascular disease 12 (12.9) 10 (9.7) 0.48
Type of admission to ICU (n, %)
 Scheduled < 0.001
  Elective surgery 4 (4.3) 23 (22.3)
 Emergency
  Ward 33 (35.5) 14 (13.6)
  Emergency department 47 (50.5) 46 (44.7)
  Emergency surgery 9 (9.7) 20 (19.4)
Diagnosis at ICU admission (n, %)
 Surgical
  Neurosurgical disease 0 (0.0) 0 (0.0) − 
  Cardiovascular disease 6 (6.5) 24 (23.3) < 0.001
  Gastrointestinal disease 6 (6.5) 17 (16.5) 0.03
  Others 1 (1.1) 2 (1.1) 0.62
 Medical
  Acute respiratory disease 43 (46.2) 30 (29.1) 0.01
  Cardiovascular disease 6 (6.5) 24 (23.3) 0.001
  Septic shock 10 (10.8) 5 (4.9) 0.12
  Post-cardiac arrest syndrome 10 (10.8) 12 (11.7) 0.84
  Trauma 9 (9.7) 5 (4.9) 0.19
  Neuromuscular disease 4 (4.3) 0 (0.0) 0.03
  Central nervous system disease 2 (2.2) 3 (2.9) 0.78
  Others 5 (5.4) 11 (10.7) 0.20
APACHE II score (mean ± standard deviation) 25.6 ± 6.6 24.3 ± 6.6 0.16
Steroid use during MV (n, %) 35 (37.6) 19 (18.5) 0.003
Neuromuscular blocker use during MV (n, %) 7 (7.5) 13 (12.6) 0.24
Vasoactive drug use during MV (n, %) 62 (66.7) 69 (67.0) 0.96
Continuous renal replacement therapy during MV (n, %) 13 (14.0) 7 (6.8) 0.10
Spontaneous breathing trail within 21 days (n, %) 38 (40.9) 85 (82.5) < 0.001
Tracheostomy (n, %) 85 (91.4) 6 (5.8) < 0.001
Time from MV initiation to tracheostomy (days; median [IQR]) 14 (9–18) 9 (7–19) 0.02
Duration of MV (days; median [IQR]) 37.0 [27.0–62.0]
ICU/HCU stay (days; median [IQR]) 34.0 [25.0–49.5] 7.0 [5.0–10.0] < 0.001
Hospital stay (days; median [IQR]) 74.0 [45.0–122.0] 35 [17.0–51.0] < 0.001
Hospital mortality (n, %) 51 (54.8) 22 (21.4) < 0.001
  1. PMV prolonged mechanical ventilation, MV mechanical ventilation, APACHE acute physiology and chronic health evaluation, IQR interquartile range, ICU intensive care unit, HCU high care unit