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Table 1 Coagulation profile before and after administration of rFVIIa

From: Successful use of recombinant activated factor VII (eptacog alfa, Novoseven®) in a refractory bleeding during pediatric cardiac surgery: a case report

  

Normal value

Before surgery

Prior to rFVIIa

1 h after rFVIIa

5 h after rFVIIa

Platelet

/μl

130–400 × 103

438,000

97,000

110,000

218,000

PT

%

80–120

53

36

>120

81

PT-INR

 

0.9–1.1

1.37

1.73

0.82

1.10

APTT

s

25–45

64

173

44

32

Fibrinogen

mg/dl

180–360

308

172

229

228

  1. rFVIIa recombinant activated coagulation factor VII, PT prothrombin time, PT-INR international normalized ratio of PT, APTT activated partial thromboplastin time