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Table 1 Results of skin tests.

From: Intraoperative chlorhexidine-induced anaphylaxis suggesting an immunoglobulin-E-dependent mechanism indicated by basophil activation tests: two case reports

Drug

SPT

IDT

Concentration of stock solution (mg/mL)

Judgment

Wheal (mm)

Flare (mm)

Concentration of stock solution (mg/mL)

Judgment

Wheal (mm)

Flare (mm)

Case 1

 Saline

9

-

  

9

-

  

 Histamine

10

 + 

6

18

0.01

 + 

10

25

 Propofol

10

-

  

1

-

  

 Rocuronium

10

-

  

0.05

-

  

 Remifentanil

0.05

-

  

0.005

-

  

 Fentanyl

0.05

-

  

0.005

-

  

 Sulbactam and cefoperazone

10

-

  

1

-

  

 Latex

NA

-

  

NA

-

  

 Chlorhexidine

5

-

  

0.002

 + 

6

20

Case 2

 Saline

9

-

  

9

-

  

 Histamine

10

 + 

5

8

0.01

 + 

9

12

 Propofol

10

-

  

1

-

  

 Rocuronium

10

-

  

0.05

-

  

 Remifentanil

0.05

-

  

0.005

-

  

 Fentanyl

0.05

-

  

0.005

-

  

 Sulbactam and ampicillin

15

-

  

1.5

-

  

 Acetaminophen

10

-

  

1

-

  

 Hydroxyethyl starch

60

-

  

6

-

  

 Chlorhexidine

5

 + 

10

12

0.002

 + 

6

10

  1. SPT reactions were deemed positive for wheal diameters ≥ 3 mm larger than that of the negative control or equal to at least half that in the positive control after 20 min. IDT reactions were deemed positive when the wheal diameter was equal to at least twice that of the post-injection wheal after 20 min [8]. SPT, skin prick test; IDT, intradermal test; NA, not applicable