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Table 3 Summary of multivariable regression model for respiratory depression

From: Postoperative respiratory depression in patients on sublingual buprenorphine: a retrospective cohort study for comparison between postoperative continuation and discontinuation of buprenorphine

Term

Estimated coefficient

95% CI lower

95% CI upper

Estimated odds ratio

P value

Intercept

−3.06

−4.57

−1.63

0.05

-

Postoperative buprenorphine continuation (yes)

−0.35

−1.12

0.39

-

0.367

Year of surgery

0.18

0.0

0.36

1.20

0.054

Facility (UWMC)

0.22

−0.39

0.82

1.25

0.468

Regional anesthesia (yes)

−0.73

−1.63

0.05

0.48

0.082

BMI, kg/m2

0.05

0.01

0.09

1.05

0.011

Preoperative antidepressant (yes)

0.73

0.17

1.30

2.08

0.010

Preoperative buprenorphine dose (≥ 16mg)

−0.92

−1.76

−0.14

-

0.025

Emergency status (yes)

−0.96

−1.77

−0.23

0.38

0.014

Postoperative buprenorphine continuation*

Preoperative buprenorphine dose ≥16mg

1.13

−0.02

2.32

-

0.058

  1. Hosmer-Lemeshow GOF X2 = 9.5 (8 df), p=0.3, c=0.72, LRT for interaction term: p=0.056
  2. Abbreviations: UWMC University of Washington Medical Center, BMI body mass index, GOF goodness of fit, LRT likelihood ratio test