The effect of anesthesia without opioid on perioperative opioid demand in children with severe obstructive sleep apnea (OSA) for adenotonsillectomies — single-center retrospective observational study

JA Clinical Reports

Table 3 Comparison of intraoperative opioid group and no intraoperative opioid group in PICU admission and non-PICU admission

		PICU admission (n=128)			Non-PICU admission (n=97)
		Anesthesia without opioid (n=56)	Anesthesia with opioid (n=72)	P value	Anesthesia without opioid (n=32)	Anesthesia with opioid (n=65)	P value
Severe pain	n (%)	28 (50%)	35 (49%)	0.88	13 (41%)	25 (39%)	0.84
Postoperative Rescue opioid	n (%)	21 (38%)	50 (69%)	<0.01	21 (66%)	45 (69%)	0.72
Postoperative opioid (mcg/kg)	Median	0	39.6	< 0.01	53.1	30.9	0.17
Postoperative opioid (mcg/kg)	Q1, Q3	(0, 57.8)	(0, 103.3)	< 0.01	(0, 246.1)	(0, 104.2)	0.17
Postoperative hypoxia requiring airway intervention	n (%)	27 (48%)	37 (52%)	0.72	5 (16%)	11 (17%)	0.87
PICU stay > 48 hours or PACU stay > 3h	n (%)	2 (4%)	5 (7%)	0.42	12 (38%)	18 (28%)	0.32
Hospital stay > 2 days	n (%)	10 (18%)	11 (15%)	0.7	1 (3%)	2 (2%)	0.98

Each incident was compared between the anesthesia without opioid and with opioid groups in PICU setting and non-PICU setting separately using the chi-square test