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Table 1 Changes in markers of coagulation and fibrinolysis

From: Treatment-resistant venous thrombosis and pulmonary embolism in a patient with granulomatosis with polyangiitis: a case report

  Entering a hospital (Day 1) Day 2 Entering the intensive care unit (Day 2) Day 3 Day 4 Day 5
Platelets (×10,000/μl) 13.4 14 10.4 8.3 6.8 4.8
Soluble fibrin (μg/ml) 61.1 41.7 20.1 10.8 16.6 19.2
D-dimer (μg/ml) 14 14.6 5.8 3.3 2.6 1.2
Prothrombin time (s) 11.7 20.5 39.3 51.4 30.5 23.8
Activated partial thromboplastin time (s) 23.9 31.6 50.7 >200 >200 >200
Fibrinogen (mg/dl) 311 350 265 273 398 392
Antithrombins (%) 96 - 98 91 54 61
Thrombin–antithrombin complex (ng/mL) 23.6 - - - - -
Plasmin–α2-plasmin inhibitor complex (μg/mL) 6.5 - - - - -
Protein S antigen level (%) 100 - - - - -
Protein C antigen level (%) 98 - - - - -