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Table 1 Perioperative coagulation tests

From: Evaluation of the effect of apixaban using a viscoelastic coagulation assay with Russell’s viper venom reagent

Coagulation test Normal range After anesthesia induction At end of surgery POD 1 POD 6
Fibrinogen (mg/dL) 150–400a 219 220 249 399
APTT (s) 24–36a 40.3 38.0 38.5 34.7
PT (%) 70–110a 42 49 59 69
PT-INR 0.9–1.1a 1.7 1.5 1.3 1.2
CT in RVV test (s) 48–77b 167 126 73 93
CT in ECA test (s) 68–100b 76 77 73 71
Anti-Xa activity (IU/mL) < 0.1b 1.69 1.12 0.06 0.78
  1. APTT Activated partial thromboplastin time, CT Clotting time, ECA Ecarin, INR International normalized ratio, POD Postoperative day, PT Prothrombin time, RVV Russell viper venom, Xa Activated factor X
  2. aBased on the institutional reference values
  3. bBased on the manufacturer’s reference values