Table 3 Patient characteristics according to the intervention with the addition of dexamethasone to periarticular anesthetic infiltration
Variable | PAI without dexamethasone (n = 55) | PAI with dexamethasone (n = 380) | P value |
|---|---|---|---|
Age, years | 75 [71, 80] | 75 [68, 80] | 0.479 |
Female sex | 48 (87.3) | 288 (75.8) | 0.060 |
Weight, kg | 58.0 [49.8, 65.6] | 61.5 [54.0, 70.4] | 0.026 |
Height, cm | 147.6 [144.0, 152.4] | 151.7 [147.0, 157.8] | 0.001 |
Body mass index, kg/m2 | 25.8 [23.7, 29.2] | 26.4 [24.1, 29.5] | 0.417 |
Diabetes mellitus | 26 (47.3) | 63 (16.6) | < 0.001 |
Insulin treatment | 6 (10.9) | 2 (0.5) | < 0.001 |
ASA-PS | 0.289 | ||
I | 0 (0.0) | 15 (3.9) | |
II | 39 (70.9) | 276 (72.6) | |
III | 16 (29.1) | 89 (23.4) | |
History of PONV/motion sickness | 7 (12.7) | 43 (11.3) | 0.821 |
Non-smoking status | 51 (92.7) | 361 (95.0) | 0.514 |
Duration of surgery, min | 114 [104, 120] | 107 [96, 120] | 0.014 |
Duration of anesthesia, min | 152 [142, 162] | 151 [138, 164] | 0.370 |
Sevoflurane use | 30 (54.5) | 192 (50.5) | 0.665 |
Propofol consumption, mg | 602 [200, 733] | 633 [200, 814] | 0.101 |
Remifentanil consumption, mg | 2.00 [1.80, 2.64] | 2.10 [1.74, 2.76] | 0.704 |
Intraoperative opioids other than remifentanil | 53 (96.4) | 361 (95.0) | 1.000 |
Intraoperative NSAIDs/acetaminophen | 42 (76.4) | 278 (73.2) | 0.744 |
Intraoperative droperidol | 39 (70.9) | 272 (71.6) | 1.000 |
Intraoperative fluid balance, ml | 760 [513, 980] | 665 [478, 885] | 0.132 |
Postoperative NSAIDs/acetaminophen | 54 (98.2) | 379 (99.7) | 0.237 |
Postoperative tramadol | 47 (85.5) | 326 (85.8) | 1.000 |
Rescue analgesic | 16 (29.1) | 30 (7.9) | < 0.001 |
Pentazocine, intravenous | 13 (23.6) | 11 (2.9) | < 0.001 |
Diclofenac, suppository | 4 (7.3) | 20 (5.3) | 0.527 |
Rescue antiemetic | 20 (36.4) | 25 (6.6) | < 0.001 |
Duration of supplemental oxygen, h | 3.0 [3.0, 3.0] | 3.0 [3.0, 3.0] | 0.799 |
PONV | 27 (49.1) | 74 (19.5) | < 0.001 |
Deep incisional or organ/space SSI | 1 (1.8) | 0 (0.0) | 0.126 |