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Table 2 Univariate analysis of hospital mortality

From: Hyperlactatemia of dialysis-dependent patients after cardiac surgery impacts on in-hospital mortality: a two-center retrospective study

 

Survivor (n = 108)

Non-survivor (n = 14)

Odds ratio

Unadjusted

95% CI

p value

Lactate value

     

 T1 (mmol/L)

1.5 (1.2, 2.1)

3.3 (1.8, 6.4)

4.18

1.91-10.0

<0.001

 T2 (mmol/L)

2.9 (2.0, 4.0)

6.4 (4.8, 10.0)

10.1

3.6-37.7

<0.001

 T3 (mmol/L)

1.6 (1.2, 2.1)

2.4 (1.7, 4.0)

4.38

1.78-12.43

0.002

 Peak time (hours)

8.0 (4.8, 14.0)

7.5 (4.0, 9.8)

0.98

0.91-1.06

0.75

Age

73 (69,77)

75 (69, 82)

1.05

0.98-1.15

0.18

Sex (male)

77 (71%)

9 (64.2%)

0.72

0.23-2.51

0.58

EF (%)

49 (37, 64)

56 (44, 60)

1.01

0.97-1.05

0.76

Years on dialysis

9 (3.5, 13.3)

13 (10, 17.8)

1.07

1.00-1.14

0.04

Preoperative complications

   

 DM

45 (42%)

5 (36%)

0.78

0.22-2.44

0.67

 Afib

30 (28%)

5 (36%)

1.44

0.41-4.54

0.54

 CI

35 (32%)

9 (65%)

3.75

1.20-13.0

0.03

 CAD

27 (25%)

4 (29%)

1.20

0.30-3.92

0.77

 ASO

25 (23%)

6 (43%)

2.49

0.75-7.85

0.12

Cause of renal failure

   

 DM

37 (33%)

6 (43%)

1.44

0.44-4.44

0.52

Procedure

     

 Valve

48 (45%)

5 (36%)

1.00

  

 CABG

11 (10%)

1 (7%)

0.87

0.04-6.17

0.91

 TAR

3 (3%)

0 (0%)

0.00

NA

0.99

 Complicated

31 (29%)

6 (43%)

1.85

0.51-6.95

0.34

 Other

15 (14%)

2 (14%)

1.28

0.17-6.64

0.78

Operating time (min)

324 (241, 395)

468 (343, 519)

1.01

1.00-1.01

0.001

CBP time (min)

176 (140, 231)

242 (187, 354)

1.01

1.00-1.01

0.003

Clamp time (min)

130 (91, 172)

170 (139, 278)

1.01

1.00-1.02

0.003

Adrenaline (yes)

9 (8%)

5 (36%)

6.11

1.60-22.12

0.006

CHDF (yes)

86 (20%)

7 (50%)

3.9

1.22-12.60

0.02

  1. Data are presented as number (%), or median (1st quartile–3rd quartile)
  2. T1 lactate at ICU admission, T2 the maximum level of lactate within 24 h postoperatively, T3 lactate at 24 h after ICU admission, EF ejection fraction, DM diabetes mellitus, Afib atrial fibrillation, CAD coronary artery disease, CI cerebral ischemia, ASO arteriosclerosis obliterans, CABG coronary artery bypass graft, TAR total arch replacement, CPB cardiopulmonary bypass, CHDF continuous hemodiafiltration