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Table 2 Comparison of selected variables in thiamylal group and propofol group

From: The effects of intravenous anesthetics on QT interval during anesthetic induction with desflurane

Variable

Group

T1

T2

T3

T4

T5

ETdes

(vol%)

T

   

3.6 (3.1–3.8 [2.7–3.9])

4.5 (4.3–4.7 [4.0–5.0])

P

   

3.3 (3.0–3.6 [2.8–3.9])

4.3 (4.0–4.6 [3.7–5.0])

BIS

T

97 (94–97 [92–98])

95 (92–97 [76–98])

45 (35–55 [21–78])*

61 (49–68 [39–76])*

57 (50–61 [39–76])*

P

95 (90–97 [91–98])

95 (91–97 [87–98])

51 (45–66 [37–88])*

40 (34–46 [26–64])*

39 (35–44 [39–76])*

HR

(min− 1)

T

69 (63–82 [46–103])

67 (58–83 [49–109])

73 (63–76 [59–101])

69 (64–73 [57–88])

68 (64–75 [52–112])

P

70 (62–79 [53–108])

67 (61–74 [56–101])

64 (59–73 [55–101])

68 (58–76 [53–87])

66 (61–72 [49–96])

MAP

(mmHg)

T

93 (86–104 [71–125])

95 (90–98 [81–142])

89 (82–99 [69–116])*

81 (72–88 [58–107])*

81 (74–90 [63–140])*

P

94 (81–102 [74–139])

90 (83–96 [70–125])

76 (64–84 [59–102])#*

69 (62–78 [51–107])#*

71 (64–85 [56–112])#*

QTcD

(ms)

T

52 (39–55 [24–74])

48 (42–62 [22–79])

44 (34–55 [24–80])

43 (34–56 [20–96])

44 (38–56 [22–72])

P

40 (34–53 [29–57])

41 (32–58 [28–90])

48 (42–62 [20–82])

39 (32–48 [22–75])

40 (31–45 [24–64])

  1. Values are median (IQR [range])
  2. T1 before fentanyl injection (baseline), T2 2 min after fentanyl injection, T3 1 min after propofol or thiamylal injection, T4 immediately before intubation, T5 2 min after intubation, ETdes end-tidal desflurane concentration, BIS bispectral index score, HR heart rate, MAP mean arterial pressure, QTcD heart rate-corrected QT interval dispersion
  3. *p < 0.05 vs. T1 values or T4 values (in ETdes); #p < 0.05 vs. thiamylal group