Skip to main content
JA Clinical Reports
Fig. 1 | JA Clinical Reports

Fig. 1

From: Andexanet alpha-induced heparin resistance treated by nafamostat mesylate in a patient undergoing total aortic arch repair for Stanford type A acute aortic dissection: a case report

Fig. 1

The chronological changes in activated clotting time (ACT) during the perioperative period. Andexanet alfa 400 mg was administered preoperatively. Heparin resistance was observed after administration of 500 IU/kg heparin before cardiopulmonary bypass. ACT was prolonged to 500 s after the administration of an initial dose of nafamostat mesilate 10 mg, followed by a continuous infusion of 20–30 mg/h. Cardiopulmonary bypass was successfully established thereafter ACT, activated clotting time

Back to article page