Total (n=210) | Robust (n=165) | Frailty (n=45) | P-value | |
---|---|---|---|---|
Age (yr) | 73 [69, 77] | 73 [69, 77] | 73 [70, 78] | 0.38 |
Male | 147 (70.0) | 123 (74.5) | 24 (53.3) | 0.01 |
Body mass index (kg/m2) | 22.9 [20.9, 24.8] | 23.1 [20.9, 24.7] | 21.9 [21.0, 25.9] | 0.80 |
ASA-PS | ||||
1 | 9 (4.3) | 7 (4.2) | 2 (4.4) | 0.73 |
2 | 170 (81.0) | 135 (81.8) | 35 (77.8) | |
3 | 31 (14.8) | 23 (13.9) | 8 (17.8) | |
Comorbidity | ||||
Symptomatic cerebral vascular disease | 10 (4.8) | 8 (4.8) | 2 (4.4) | > 0.99 |
Hypertension | 117 (55.7) | 90 (54.5) | 27 (60.0) | 0.61 |
Ischemic heart disease | 12 (5.7) | 11 (6.7) | 1 (2.2) | 0.46 |
Peripheral arterial disease | 1 (0.5) | 1 (0.6) | 0 (0.0) | > 0.99 |
Diabetes | 53 (25.2) | 40 (24.2) | 13 (28.9) | 0.56 |
Medication | ||||
β-blocker | 11 (5.2) | 6 (3.6) | 5 (11.1) | 0.06 |
Steroid | 3 (1.4) | 3 (1.8) | 0 (0.0) | > 0.99 |
Statin | 57 (27.1) | 42 (25.5) | 15 (33.3) | 0.34 |
Laboratory data | ||||
Serum albumin (g/dL) | 4.2 [4.0, 4.4] | 4.3 [4.1, 4.5] | 4.1 [3.7, 4.2] | <0.001 |
Serum creatinine (mg/dL) | 0.80 [0.67, 0.99] | 0.81 [0.68, 1.00] | 0.77 [0.65, 0.93] | 0.18 |
Intraoperative covariate | ||||
Anesthetic agents | ||||
Inhalation agents | 203 (96.7) | 160 (97.0) | 43 (95.6) | 0.64 |
Intravenous agents | 7 (3.3) | 5 (3.0) | 2 (4.4) | |
Surgical field | 0.13 | |||
General | 155 (73.8) | 121 (73.3) | 34 (75.6) | |
Urologic | 49 (23.3) | 41 (24.8) | 8 (17.8) | |
Gynecologic | 6 (2.9) | 3 (1.8) | 3 (6.7) | |
Insertion of arterial catheter | 167 (79.5) | 129 (78.2) | 38 (84.4) | 0.41 |
Total fluid volume (mL) | 2300 [1750, 3300] | 2250 [1745, 3262] | 2500 [1912, 4087] | 0.21 |
Ephedrine (mg) | 14.0 [8.0, 24.0] | 12.0 [6.0, 24.5] | 16.0 [8.0, 21.0] | 0.71 |
Phenylephrine (mg) | 0.10 [0.0, 0.75] | 0.10 [0.0, 0.56] | 0.30 [0.0, 0.85] | 0.26 |
Postoperative analgesia | 0.06 | |||
None | 2 (0.9) | 1 (0.6) | 1 (2.2) | |
PCEA | 95 (45.2) | 75 (45.5) | 20 (44.4) | |
IV-PCA | 113 (53.8) | 89 (53.9) | 24 (53.3) | |
Surgical duration (min) | 298 [217, 375] | 288 [216, 375] | 323 [219, 387] | 0.63 |
Blood loss volume (mL) | 66 [17, 250] | 51 [15, 225] | 165 [65, 290] | 0.01 |
Surgical Apgar score | 8.0 [7.0, 8.0] | 8.0 [7.0, 8.0] | 7.0 [7.0, 8.0] | 0.03 |